{"id":8561,"date":"2015-09-11T06:50:21","date_gmt":"2015-09-11T06:50:21","guid":{"rendered":"http:\/\/www.times.mw\/?p=8561"},"modified":"2015-09-11T06:50:21","modified_gmt":"2015-09-11T06:50:21","slug":"is-it-time-to-make-designer-babies","status":"publish","type":"post","link":"https:\/\/archive.times.mw\/index.php\/2015\/09\/11\/is-it-time-to-make-designer-babies\/","title":{"rendered":"Is it time to make designer babies?"},"content":{"rendered":"<p class=\"story-body__introduction\">Scientists say it may be &#8220;morally acceptable&#8221; to create genetically modified babies in the future and say it is &#8220;essential&#8221; that they are allowed to experiment on embryos.<\/p>\n<p>So why is this suddenly an issue and what could it mean for society?<\/p>\n<h2 class=\"story-body__crosshead\">What&#8217;s a designer baby?<\/h2>\n<p>Well it is like a normal baby, but one that has been modified by altering their DNA &#8211; which is the blueprint for building a person.<\/p>\n<h2 class=\"story-body__crosshead\">So what could you change?<\/h2>\n<p>Your DNA blueprint is far from perfect. Lots of diseases such as <a class=\"story-body__link-external\" href=\"http:\/\/www.cysticfibrosis.org.uk\/about-cf\/what-is-cystic-fibrosis\">cystic fibrosis,<\/a><a class=\"story-body__link-external\" href=\"http:\/\/www.scid.net\/\">bubble boy syndrome<\/a> (Severe Combined Immunodeficiency Disease) and the blood disorder <a class=\"story-body__link-external\" href=\"http:\/\/www.nhs.uk\/conditions\/Thalassaemia\/Pages\/Introduction.aspx\">beta thalassaemia<\/a> are down to bad instructions in your DNA.<\/p>\n<p>These defects could be corrected.<\/p>\n<p>But a baby could in theory also be engineered to resist diseases. A single mutation can protect against HIV infection and there are also sections of your DNA which increase the risk of cancer which could also be altered.<\/p>\n<p>Then there&#8217;s the far more distant prospect of making alterations to alter height, beauty, hair colour or intelligence.<\/p>\n<h2 class=\"story-body__crosshead\">Whoa! Is this possible now?<\/h2>\n<p>Nobody is on the cusp of doing this.<\/p>\n<p>However, genetic engineering is progressing at a phenomenal pace and scientists say it is important to discuss what is acceptable now, rather than wait until someone crosses an ethical line.<\/p>\n<p>Earlier this year Chinese scientists corrected the defect causing beta thalassaemia in embryos (they were then destroyed rather than implanted).<\/p>\n<h2 class=\"story-body__crosshead\">Why are we talking about this now?<\/h2>\n<p>A few years ago a new way of editing DNA was discovered. It has transformed research and is now being used by biology laboratories around the world, whether they&#8217;re working on plants, animals or human embryos.<\/p>\n<p>The method combines a &#8220;molecular sat-nav&#8221; that travels to a precise location in our DNA with a pair of &#8220;molecular scissors&#8221; that cut it.<\/p>\n<p>But that&#8217;s a simple description.<\/p>\n<h2 class=\"story-body__crosshead\">So what&#8217;s a more technical one?<\/h2>\n<p>The main method being used is called <a class=\"story-body__link-external\" href=\"https:\/\/www.youtube.com\/watch?v=2pp17E4E-O8\">CRISPR-Cas9<\/a> and it is the way bacteria defend themselves against viruses.<\/p>\n<p>A short section of genetic material precisely matches up with a section of DNA and then the enzyme Cas9 comes along and makes a cut.<\/p>\n<p>Your DNA then tries to repair itself &#8211; this can turn off that section of DNA or allow scientists to insert new sections of DNA that they have engineered.<\/p>\n<p>And it is cheap. And it is easy.<\/p>\n<p>There are other techniques such as Zinc Fingers and Talens which have some advantages, but are harder to perform.<\/p>\n<h2 class=\"story-body__crosshead\">Are designer babies acceptable?<\/h2>\n<p>Well that&#8217;s for you to decide, but in the eyes of the law at the moment then &#8216;no&#8217;.<\/p>\n<p>But it is worth noting the UK has already made a big shift &#8211; in 2015 it made the historic decision to allow the creation of babies <a class=\"story-body__link\" href=\"http:\/\/www.bbc.co.uk\/news\/health-31069173\">with DNA from two women and one man<\/a>.<\/p>\n<p>The reason was to prevent babies being born with &#8220;mitochondrial diseases&#8221;.<\/p>\n<p>It was the source of vigorous ethical debate &#8211; and it&#8217;s one we may be hearing again soon.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists say it may be &#8220;morally acceptable&#8221; to create genetically modified babies in the future and say it is &#8220;essential&#8221; that they are allowed to experiment on embryos. So why is this suddenly an issue and what could it mean for society? What&#8217;s a designer baby? Well it is like a normal baby, but one [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-8561","post","type-post","status-publish","format-standard","hentry"],"_links":{"self":[{"href":"https:\/\/archive.times.mw\/index.php\/wp-json\/wp\/v2\/posts\/8561","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/archive.times.mw\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/archive.times.mw\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/archive.times.mw\/index.php\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/archive.times.mw\/index.php\/wp-json\/wp\/v2\/comments?post=8561"}],"version-history":[{"count":0,"href":"https:\/\/archive.times.mw\/index.php\/wp-json\/wp\/v2\/posts\/8561\/revisions"}],"wp:attachment":[{"href":"https:\/\/archive.times.mw\/index.php\/wp-json\/wp\/v2\/media?parent=8561"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/archive.times.mw\/index.php\/wp-json\/wp\/v2\/categories?post=8561"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/archive.times.mw\/index.php\/wp-json\/wp\/v2\/tags?post=8561"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}